University of Maryland

Marlene & Stewart Greenebaum Comprehensive Cancer Center (UMGCCC)

FY27 Pilot Grant Program

Shared Resource & Research Infrastructure Development Award

Purpose

The Shared Resource & Research Infrastructure Development Award supports the expansion, enhancement, or creation of UMGCCC Shared Resources or cancer‑relevant research infrastructure that broadly benefits investigators.

Eligibility

• Principal Investigators (PIs) must be Program in Oncology (PIO) members in good standing as indicated in the membership guidelines (regular participation in programmatic seminars and events, pilot project reviewer, participation in surveys, mentor trainees, etc.).
• UMGCCC Research Program Leaders are eligible to serve as PI, but must be in a MPI structure across either 1.) a minimum of 2 Research Programs or 2.) 1 Research Program and 1 Shared Resource.

Award Information

• No fixed budget limit
• Funds must be expended within 12 months from start date

Application Requirements

• Applications for expanded Shared Resources, or new Shared Resources, should discuss the benefits and provide a quantitative justification that will support new cancer research or support. 
• Applications that propose infrastructure improvements should be fully justified and should include a rationale for that support. 
• Applicants are encouraged to expand state of the art research capabilities and access to the shared resources, including but not limited to: 
  • Population science and clinical research infrastructure
  • Structural biology
  • High-dimensional single-cell and spatial immune profiling
  • Data infrastructure and analytic pipelines
  • Automation and cost reimbursement/revenue generating models
• Applications are encouraged to defray the cost for developing new research aims that exploit the state-of-the-art capabilities of our Shared Resources, and when appropriate, share data within emerging data infrastructure developing in the UMGCCC Shared Resource.
• Applications for large or unique pieces of equipment will be considered only if other sources of support (e.g., an NIH S10) have been previously submitted and scored.

General Application Components

Unless specifically stated, title page (including names of key personnel, project title, PIO program(s) affiliated and Shared Resources used), 5 page maximum single spaced, excluding references, budget, budget justification and biosketches.

• Title Page
  • PIO Program
  • Principal Investigator(s)
  • Other Key Personnel
• Specific Aims and Hypotheses (1 page)
• Research Strategy (5 page maximum single spaced)
  • Background and Significance – include rationale, significance, innovation, how results will support an application for external funding
  • Scientific Approach – include overall design, participant eligibility, data collection, intervention (if appropriate), data analysis plan, statistical power/sample size justification, strengths, and limitations
• Budget (NIH 398 format) – faculty salary is not allowable; staff salary is allowable at a maximum 25%
• A current Biosketch, including biosketches for Key Personnel – use NIH style
• Scores and reviewer comments for Payline Program Applications
• References

General Review Criteria

• Significance – Does the research address an important cancer related scientific question and support the mission of the UMGCCC? Will support lead to a multi-PI, U01, P01, SPORE or similar applications for external funding? Will it lead to peer-reviewed publications?
• Relevance – Does the proposed project address one or more of key determinants of cancer outcomes relevant to UMGCCCC catchment area including cancer biology, prevalence and incidence, prevention, treatments, care access, geography, outcomes, and survivorship relevant to specific communities?
• Approach – Are the design and methods appropriate, and can the research be completed within the proposed period?
• Innovation – Are scientific questions and/or approaches novel?
• Investigators – Are the researchers qualified, and does the team include one or more
• collaborations among PIO research programs?
• Environment – Is the environment supportive and are UMGCCC Shared Resources used?

General Award Conditions

Applications that span more than one PIO research program are strongly encouraged. The application must demonstrate how funds will be spent in a 12-month period, unless stated specifically in the RFA.

• Unspent funds cannot be carried forward.
• Applicants are responsible for cost overruns.
• Any unallowable expenses will become the responsibility of the recipients.
• F&A costs (indirect costs) will not be provided.
• Reasonable staff salaries including salary for graduate research assistants will be funded at a maximum of 25%. Faculty salaries will not be permitted.
• Funding requests for travel (except Fellowship awards), membership, subscriptions and telecommunications are not permitted.
• Applicants are solely responsible for having appropriate institutional approvals (IRB, IACUC, EHS, etc.) before projects are undertaken.

General Reporting Requirements

The Cigarette Restitution Fund and the NCI Cancer Center Support Grant, both of which fund this initiative, include strict reporting requirements. Be sure to carefully cite & track publications, research applications, patents, inventions, collaborations, etc. that come to fruition because of this funding as you will be contacted annually by the administration for the collection of this information. A one to two-page final scientific report will be required within 90 days of the close of the pilot project.

General Mandatory Citations

All efforts resulting from this funding opportunity must include the following citations:

• This (article, conference, publication, etc.) was supported by funds through the Maryland Department of Health Cigarette Restitution Fund Program – CH-649-CRF.
• This (article, conference, publication, etc.) was supported by funds through the National Cancer Institute – Cancer Center Support Grant (CCSG) – P30CA134274.

Questions and Submission Method

• Questions about the RFA should be addressed to Sarah Laye, UMGCCC Assistant Director for Administration at slaye@som.umaryland.edu.